Go to Home Page
Main Message Board | Treatment Discussions | Polls | MC FAQs | Recipes | Information Sites | Medication Info | Diet Info | Jokes | Photo Gallery
  Username:    Password:      Remember me       
MICROSCOPIC COLITIS SUPPORT Forum Index

You can get your life back
MICROSCOPIC COLITIS SUPPORT
Discussion and Support Forum for Collagenous Colitis, Lymphocytic Colitis, Microscopic Colitis, Mastocytic Enterocolitis, and Related Issues

MICROSCOPIC COLITIS SUPPORT Forum IndexVisit the Microscopic Colitis Foundation Website
 

The only comprehensive book ever written about Microscopic Colitis
Can be ordered at any bookstore or library
 FAQFAQ  RulesRules   SearchSearch   MemberlistMemberlist   UsergroupsUsergroups  ChatChat   RegisterRegister 
 ProfileProfile   Log in to check your private messagesLog in to check your private messages   Log inLog in 
 World Time Clock--Time ZonesPotty People T-ShirtsPrivacy Policy
Google
SearchSearch The Archives of This Discussion Board
Anti-Actin Antibody: should it be part of the MC work-up?

 
Post new topic   Reply to topic       MICROSCOPIC COLITIS SUPPORT Forum Index -> Polls Related to Microscopic Colitis and Treatment Options
 View previous topic :: View next topic  

Have you been tested for Anti-Actin Antibody?
Yes, and it was positive
10%
 10%  [ 2 ]
Yes, and it was negative
0%
 0%  [ 0 ]
No
90%
 90%  [ 18 ]
Not sure
0%
 0%  [ 0 ]
Total Votes : 20

Author Message
Zizzle
King Penguin
King Penguin


Joined: 22 Jul 2010

Posts: 3483
User's local time:
2017 Sep 26 - 4:07 AM


Food Intolerances : gluten, dairy, soy, sesame seeds, buckwheat, amaranth, walnuts, peppers, CORN!

PostPosted: Thu Apr 28, 2011 9:42 am    Post subject: Anti-Actin Antibody: should it be part of the MC work-up? Reply with quote

I had high levels of Anti-Smooth Muscle Antibody 6 years ago. Around the time of my LC diagnosis 2 years ago, the ASMA test was replaced by the Anti-Actin Antibody test, which essentially tests the same thing, but with more specificity. I was positive then, and again last year just after starting the GF/DF/SF diet. I've known these antibodies are tied to Autoimmune Hepatitis (I like to think of it as celiac hepatitis now - something I hope to be preventing). But Anti-Actin is apparently also being considered to diagnose celiac disease!! Of course Dr. Fasano didn't seem phased by my results and didn't repeat them in his celiac work-up, so I guess the science isn't all there yet, but he did write an article on Medscape about it. Has anyone else had the anti-Actin antibody test??

Could it be a marker for the mucosal damage caused by MC, not just celiac? Should it become part of the diagnostic work-up for MC?

Quote:
Dr. Fasano:

The anti-actin antibody assay represents the most recent addition to the "diagnostic arsenal" in celiac disease. It was recently reported that this test is particularly sensitive in detecting cases of celiac disease characterized by severe intestinal mucosal damage, with a reported sensitivity of 100%.[8] If these data are confirmed, it may be possible to devise a stepwise protocol in which symptomatic patients who test tTG-positive (and subsequently anti-actin antibody positive) can avoid intestinal biopsy for diagnostic confirmation.


http://www.medscape.org/viewarticle/505105
Back to top
Zizzle
King Penguin
King Penguin


Joined: 22 Jul 2010

Posts: 3483
User's local time:
2017 Sep 26 - 4:07 AM


Food Intolerances : gluten, dairy, soy, sesame seeds, buckwheat, amaranth, walnuts, peppers, CORN!

PostPosted: Fri Oct 19, 2012 11:26 am    Post subject: Reply with quote

Moving up this post in case any newbies want to answer the poll. Anti-Actin Antibody is also known as Anti-Smooth Muscle Antibody (ASMA or SMA).
Back to top
Noodler
Little Blue Penguin
Little Blue Penguin


Joined: 12 Aug 2011

Posts: 48
User's local time:
2017 Sep 26 - 9:07 AM


Food Intolerances : Meats, Lots of Fruit and Veg, Grains, probably Gluten...the kitchen sink
Location: UK

PostPosted: Fri Oct 26, 2012 9:51 am    Post subject: Reply with quote

Hi Zizzle, I had positive ASMA levels on a couple of occasions. Not had anti-actin antibody test but have also had elevated liver panel tests.
Back to top
Zizzle
King Penguin
King Penguin


Joined: 22 Jul 2010

Posts: 3483
User's local time:
2017 Sep 26 - 4:07 AM


Food Intolerances : gluten, dairy, soy, sesame seeds, buckwheat, amaranth, walnuts, peppers, CORN!

PostPosted: Fri Oct 26, 2012 10:07 am    Post subject: Reply with quote

Hi Noodler,
Have they told you have autoimmune hepatitis? Are they monitoring your liver enzymes to catch it if it develops?
Back to top
PJ
Little Blue Penguin
Little Blue Penguin
United States

Joined: 16 Sep 2012

Posts: 46
User's local time:
2017 Sep 26 - 3:07 AM


Food Intolerances : Unknown

PostPosted: Fri Oct 26, 2012 5:27 pm    Post subject: Reply with quote

In my case, I am not even convinced now that I DON'T have celiac also since my new GI doc who ordered the MC biopsy could not obtain the records from my old GI practice (they merged with another practice) My only celiac bloodwork is several years old now and now inaccessible for some reason. Should I talk to my new Gi doc for this anti-actin autobody test to see if I actually could have celiac also? Being Type 1 diabetic, I am kind of surprised if I don't have celiac. After my recent sigmoidoscopy I would like to avpid another in-hospital procedure! I do plan on having Dr. Fine's lab run all the tests for me as soon as my HSA benefits and new insurance kicks in.

Thanks,

Pam
Back to top
Zizzle
King Penguin
King Penguin


Joined: 22 Jul 2010

Posts: 3483
User's local time:
2017 Sep 26 - 4:07 AM


Food Intolerances : gluten, dairy, soy, sesame seeds, buckwheat, amaranth, walnuts, peppers, CORN!

PostPosted: Sat Oct 27, 2012 7:10 am    Post subject: Reply with quote

I doubt any doctors are using this or the anti-actin test to help diagnose celiac disease, but if you don't have results, it wouldn't hurt to get the traditional celiac tests. Enterolab results will be most informative.
Back to top
PJ
Little Blue Penguin
Little Blue Penguin
United States

Joined: 16 Sep 2012

Posts: 46
User's local time:
2017 Sep 26 - 3:07 AM


Food Intolerances : Unknown

PostPosted: Mon Oct 29, 2012 10:17 am    Post subject: Reply with quote

Thanks Zizzle,

Yes, I have planned on Enterolab testing as soon as I can swing it. I am pretty sure my new GI doc will order a new set of celiac labs also when I visit her again.

Cheers,

Pam
Back to top
Display posts from previous:   
Post new topic      Reply to topic    MICROSCOPIC COLITIS SUPPORT Forum Index -> Polls Related to Microscopic Colitis and Treatment Options All times are GMT - 6 Hours
Page 1 of 1

 
Jump to:  
You cannot post new topics in this forum
You cannot reply to topics in this forum
You cannot edit your posts in this forum
You cannot delete your posts in this forum
You cannot vote in polls in this forum

Remove cookies set by this forum

Search online dictionaries
(Powered by OneLook® Dictionary Search)
Enter word or phrase:
Enter a word to search for dictionary web sites that include that word.
Enter a pattern consisting of letters and wildcards to search for words.
Valid wildcards are * (matches multiple letters) and ? (matches one letter).
Locations of visitors to this page


Powered by phpBB © 2001, 2005 phpBB Group
IP Country Flag 2.9.6b © 2005, 2008 - 3Di (aka 3D)

Copyright 20052017 perskyfarms.com, All Rights Reserved

Copyright Notice: The material on this site is copyrighted by perskyfarms.com, and it is protected from unauthorized copying and dissemination by United States copyright law, trademark law, international conventions, and other intellectual property laws. This copyright protection also extends to any and all images, found on any and all pages of this site.

Please contact us at this address for permission, if you wish to use any material on this website for any commercial or public purpose.

We have made a good faith effort not to violate any copyright. If we have unknowingly done so, please contact the site administrator, at this address, and the issue will be promptly corrected.

Disclaimer: The information contained within this site is intended solely for general educational purposes, and is not intended, nor implied, to be a substitute for professional medical advice relative to your specific medical condition or question. Anyone who chooses to use any information found here, does so at his or her own risk. Always seek the advice of your physician or other health care provider for any questions you may have regarding your medical condition. Only your physician can provide specific diagnoses and therapies. By using this site you agree to the following terms and conditions:

Certain members of this discussion board are practicing medical professionals. They are not here to offer medial advice, they are here because they have been diagnosed with microsopic colitis, and they are interested in sharing their own personal experiences concerning the disease, and learning from others in all walks of life, who also have to deal with these issues. If you have any questions or concerns regarding your health, you should consult with your own doctor, or medial professional.

If you think you may have a medical emergency, call your doctor, or 911, immediately. The members of this board, regardless of whether or not they are medical professionals, cannot respond to issues requiring urgent medical attention. Please note that no legal action can be taken by any user of this site, as a result of any information found here, and that none of the parties involved, neither individually, nor collectively, nor the owner of this site, can be held responsible for any information offered in the course of discussions, regardless of circumstances, whether those discussions are in a public or private form, and regardless of whether of not any of the parties involved are professionals. Remember that this discussion board is not intended to be a replacement for a consultation with your doctor or other medical professonal, it is intended as a sharing of knowledge and information from the research and personal experience of the members of this discussion board.

This site does not recommend or endorse any specific tests, products, procedures, opinions, or other information that may be mentioned anywhere on this site. Reliance on any information provided here is solely at your own risk.

Main Message Board | Treatment Discussions | Polls | MC FAQs | Recipes | Information Sites | Medication Info | Diet Info | Jokes | Photo Gallery