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Do You Believe That Your MC Was Caused By Antibiotics?
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Do you feel that one or more antibiotics played a signifiant role in the development of your MC?
Yes, I believe that antibiotics caused my MC
25%
 25%  [ 17 ]
Probably, but I can't be sure, because there were other possible triggers, also
14%
 14%  [ 10 ]
It's impossible for me to tell, one way or the other
10%
 10%  [ 7 ]
Probably not, because I'm fairly sure that my MC was caused by something else
22%
 22%  [ 15 ]
No, I'm sure my MC was caused by something else
26%
 26%  [ 18 ]
Total Votes : 67

Author Message
tex
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Joined: 24 May 2005

Posts: 30706
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2017 Nov 18 - 7:44 AM


Food Intolerances : Gluten, casein, soy, and avenin, (avenin is the prolamin in oats, which is equivalent to the gluten in wheat), beef, grapes, peanuts, cashews, almonds, (but nut butters seem OK except for peanuts), citric acid, chocolate, and agar.
Location: Central Texas

PostPosted: Sat Oct 22, 2011 9:45 pm    Post subject: Do You Believe That Your MC Was Caused By Antibiotics? Reply with quote

Hi All,

It's well known that antibiotics can wreak havoc with our intestinal bacteria, causing all sorts of problems that can range from a C. diff infection to MC, and various other problems. Once the gut bacteria populations are altered, it's usually impossible to restore them exactly as they were, originally. Obviously, this can lead to long-term problems, and some of us have developed MC soon after taking an antibiotic, while others have developed the disease later, or after taking a series of antibiotic treatments.

Of course, there are many other possible triggers for the disease, so please select the option in this poll, that seems to fit your situation best.

Thanks,
Tex
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It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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sarkin
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Joined: 10 Mar 2011

Posts: 2313
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Food Intolerances : Gluten, dairy, eggs (maybe more?)
Location: Brooklyn, NY

PostPosted: Sat Oct 22, 2011 10:23 pm    Post subject: Reply with quote

I do believe that doxycycline was a contributing factor for me. I think 'cause' is a strong word Laughing - and there was a trifecta (superfecta?) of other events happening around that time, but I do believe that the doxycycline was caught red-handed.

There was also a lot of hormonal upheaval, as I'd just had my first miscarriage; codeine (my first ever experience of C), a possible C.diff Dx; and I had quit smoking some months before - and I had been taking a lot of Ibuprofen.

In retrospect, if I had been a lab rat, I had the perfect method devised to 'cause' MC...
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Gabes-Apg
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Food Intolerances : Gluten, Yeast, Caesin, Soy, salad/raw veges and fruit
Location: Hunter Valley NSW Australia

PostPosted: Sat Oct 22, 2011 11:09 pm    Post subject: Reply with quote

My IBS got worse and I started to have what i now know to be MC related symptoms after I had considerable intake of doxycycline over a 12 month period.
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harma
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Joined: 04 Oct 2009

Posts: 984
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2017 Nov 18 - 3:44 PM


Food Intolerances : lactose, caseine, soy, gluten, yeast, probalby egg (enterolab testing) also problems digesting corn, mushrooms, pepers.
Location: amman

PostPosted: Sun Oct 23, 2011 4:49 am    Post subject: Reply with quote

I voted for "its impossible for me to tell", just simply because I don't know. But thinking deeper, it could very well be. From my teenagers years, let see 16/17 years until about 2003/2004, so that till I was about 35/36 years I have had a lot of antibiotics cures, like one/twice and in bad cases three times a year. Everytime I got a cold, I got a sinus infection. As a child, as far as I can remember I did not have real bowel issues. So, yes it could very well be that almost 20 years of two/three times a year having antibiotics for about a week had influence on my gut flora and maybe were also of influence of the MC.

But personally I would vote for gluten intolerance. I am 100% sure that I am intolerant to gluten. But than why did it only start bothering about 10 years ago....that question I can't answer, maybe because of changes in the gut flora???

What would be interesting if a scientist would invest the composition of bacteria in our intestine. This week I saw a very interesting documentary on the latest development on our inhibitors of our intestine. We seem to have about 100 billion bacteria in our intestine (about one kilo of our body mass). Researchers are now typing this and we all seem to have our unique bacterial composition in our gut (like a finger print or our DNA, that unique), and also there seem to be three basic types of bacterial composition (almost like blood types). What I also remembered that with some disease, certain bacteria were lacking (or on the other hand more present) in the big bowel. They even start linking depression to inhibitors of our gut.

The other part of the documentary was about parasites. The idea is that one reason, we have so many auto immune disease nowadays is, because we got rid of all the parasites in our intestines (like worms). The idea of the immune system was then busy with all those parasite, so "did not have to time" to attack the body. I just don't like this explanation, because it comes up with terms as "an immune system is bored and looks for something to do" "or is too busy with...", as is the immune system is an independent being and not part of the whole human body system.

But one explanation did make sense (at least to me), the worms in the intestine are parasites and do everything to survive in there. One of their survival mechanism is to excrete chemical compounds that suppress the immune system in the intestine. That makes more sense to me than just expression as "immune system is bored". Our whole body is a chemical factory, with balance and disbalance and action and reaction.



I could put a link to the documentary here, but I think it is useless since it is all in Dutch.
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Deb
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Joined: 20 Nov 2010

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Food Intolerances : Gluten, still determining others
Location: Minnesota

PostPosted: Sun Oct 23, 2011 5:14 am    Post subject: Reply with quote

I haven't used an antibiotic for a number of years so I'm sure mine wasn't triggered by that. Now stress, that's another matter.
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Polly
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Joined: 25 May 2005

Posts: 5165
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Food Intolerances : gluten, dairy, soy, corn, yeast, chocolate, tomato, white potato, celery, sesame, carrot, yellow squash, lamb, pork, mango, strawberry, almond, cashew, vanilla, grapefruit, raspberry, avocado, mustard, paprika, cauliflower, cucumber, plum, and more!
Location: Maryland

PostPosted: Sun Oct 23, 2011 7:30 am    Post subject: Reply with quote

Another vote for doxycycline here! I'm sure it was the primary trigger for my MC. I find the above comments most interesting, in view of the fact that doxycycline is not generally one of the more commonly--used antibiotics - especially not for the common URIs, sinus infections, skin infections etc. Hmmmmm. Good poll, Gloria and Tex.

Harma, I couldn't agree more that the answer may lie with the gut bacteria. I'm so glad that research on this is underway. Bacteria are fascinating, and we are only beginning to understand how they work. I've heard that they can even "talk" to each other, by chemical means, I guess.

I think there could be some truth to the idea that AI diseases result from a "bored" immune system, one that doesn't have enough to do. And I'm not so sure that the immune system doesn't "have a mind of its own". Several years ago I watched a movie of a real-life white cell pursuing a bacterium in a blood vessel. Of course, it was happening under a microscope. You would not have believed the single-minded determination, speed, and endurance of this single white cell as it chased the bacterium until it finally engulfed it. That white cell seemed like an action hero - incredibly powerful. If there are no longer enough bacteria to attack in modern days, these powerful warriors could indeed attack other/normal cells, IMHO. You would have to see this movie to believe it!

Worms are another story. I think some have treated gut diseases by giving the patient worms. Who knows? Maybe we are meant to live symbiotically with intestinal worms? Perhaps their role IS to reduce inflammation, as you suggest.

Deb, we now know that stress can alter the gut bacteria negatively, so that may be the mechanism for stress-induced colitis/flare.

Hugs,

Polly

P.S. It would be interesting to find out the specific gut bacteria that are wiped out by doxycycline. Maybe we could try to replace it probiotically
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misslilly



Joined: 17 Oct 2011

Posts: 11
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Food Intolerances : Dairy,Gluten

PostPosted: Sun Oct 23, 2011 8:00 am    Post subject: Reply with quote

I went to the Dr's for sinus infection this wk. He put me on a steroid pack instead of antibiotics because of my colitis.

My elderly Mom has D issues. I have finally gotten her to believe dairy is a problem for her lifetime gas issues. My memories of her is a bottle of mylanta in every room of the house when I was a child. She feels alot better now but I wish she would realise gluten is a problem too. It is hard to teach old dogs new tricks:)
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Gloria
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Joined: 07 Jul 2007

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Food Intolerances : gluten, soy, casien, eggs, legumes, Pepto Bismol, all fruit except mango, all vegetables, tomatoes, onions, peppers, carrageenan, chicken, beef, orange roughy, cucumber, vinegar, chocolate, olives, buckwheat, millet, tapioca, sorghum, rice
Location: Illinois

PostPosted: Sun Oct 23, 2011 5:39 pm    Post subject: Reply with quote

Yes, I took both flagyl and levaquin for a diverticulitis attack. I had non-stop D within a few days of starting the regimen. My daughter with "IBS" told me to stop taking the antibiotics. Instead, I called the doctor and told him what was happening. He told me that neither antibiotic should cause D and said I should continue taking them for the entire two weeks. Unfortunately I followed his advice and had D for five weeks.

I had a reprieve for several weeks and was back to normal. Then, I took another antibiotic after having foot surgery. A month or so later, I began having relentless D and eventually was diagnosed with MC. I always ate yogurt while taking antibiotics, but it obviously wasn't enough.

Gloria
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Lesley
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Joined: 03 Sep 2011

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Food Intolerances : Too many to list

PostPosted: Sun Oct 23, 2011 6:58 pm    Post subject: Reply with quote

I had a couple of years during which I had UTIs at least every month, treated with antibiotics. However, I was also taking PPIs and antidepressants and other stuff, so for me it has to be a mixture of everything.
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Sheila
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Joined: 18 May 2011

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Food Intolerances : gluten, eggs, cow's milk, soy, guar gum, whey, goat's milk, cocoa, crab, carrot, amaranth, kamut,
Location: Palm Beach Gardens, Fl

PostPosted: Sun Oct 23, 2011 7:07 pm    Post subject: Reply with quote

Two and 1/2 yrs ago I had an ear infection, went to the local walk-in clinic and was given an antibiotic. I took it for a day or two and started with horrible D. Called the clinic and they changed the meds. The D continued until I ended up in the ER completely dehydrated. DH was out of town on business or he would have had me in the hospital before I passed out. I don't remember which anti-biotic I was given. The D stopped for a week while I was in Italy because of massive doses of immodium and another drug, can't remember name. Since then the D started and stopped until it erupted in all it's glory last December. Originally my doctor thought I had C diff. In retrospect, it was the first full blown flare of CC. With my genes, it was bound to happen sooner or later.
Sheila
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harma
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Joined: 04 Oct 2009

Posts: 984
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2017 Nov 18 - 3:44 PM


Food Intolerances : lactose, caseine, soy, gluten, yeast, probalby egg (enterolab testing) also problems digesting corn, mushrooms, pepers.
Location: amman

PostPosted: Mon Oct 24, 2011 1:46 am    Post subject: Reply with quote

I have used doxycycline a lot for my sinus infections over the years.
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brandy
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Joined: 16 Oct 2011

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Food Intolerances : gluten, dairy, soy, corn, sugar, quinoa, rasberries, blackberries
Location: Florida

PostPosted: Mon Oct 24, 2011 3:01 pm    Post subject: Reply with quote

Nope, mine was directly caused by "overeating." Learned the glutton (as in gluttony) lesson big time.
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Robin
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Joined: 11 Oct 2011

Posts: 228
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2017 Nov 18 - 8:44 AM


Food Intolerances : Gluten, dairy, soy, corn, chicken, tuna, pork, cashews, casein and probably more!
Location: Wantagh

PostPosted: Mon Oct 24, 2011 6:06 pm    Post subject: Reply with quote

I have not been on any type of antibiotics for a very long time. However, I was taking large doses of Advil for almost 3 years. I was in a car accident and did not like taking prescription pain killer. I also had food poisoning 5 years ago, which landed me in the hospital.

Best of health
Robin
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paceys wife

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Joined: 13 Oct 2011

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PostPosted: Wed Oct 26, 2011 6:56 pm    Post subject: Reply with quote

I lean a bit towards yes in the antibiotics. I was recently diagnosed with LC. In Jan 2011, I was diagnosed with Lyme's after complaining of joint pain (I thought it was arthritis) and was put on Doxycycline. In March, I had a peritonsillar abscess. I had two courses of IV antibiotics, clindamyacin and steroids. In June, my son tested positive for pertussis (even though vaccinated) and we were all put on an antibiotic. To top it all off, in July, I was stung by a bee and developed cellulitis in my elbow. Two more courses of IV antibiotic and an oral! The D actually started in June but lasted through mid-September...thus the visit to GI after I could no longer deal with the symptoms.

It's been a crazy 2011...
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carolm
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Joined: 02 Sep 2011

Posts: 1004
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2017 Nov 18 - 7:44 AM


Food Intolerances : Enterolab: gluten, soy, dairy, eggs, pork. MRT- Reds: Cola. Yellows: Capsaicin, sorbic acid, ibuprofen, Blue #2, maple, cherry, peach, pineapple, grapefruit, plum, papaya, pear, beet, string beans, cucumber, green pea, lima bean, walnut, tea.
Location: Kansas City

PostPosted: Fri Oct 28, 2011 7:01 pm    Post subject: Reply with quote

HI All,
I'm going to say 'no' on the antibiotics, but I was taking Ibuprofen frequently in the winter and spring due to sinus headaches, plus I was on Zocor ( a statin drug to reduce cholesterol). I'm thinking these two things plus who knows what else contributed to my LC.

Carol
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